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Search Results for " fc gamma receptor iib "

Targets Recommended: Others

4

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9543	Syk Inhibitor II hydrochloride	Others	Others
	Syk Inhibitor II hydrochloride 信号传导的影响在狼疮中可能很突出。
T4391	Syk Inhibitor II dihydrochloride Syk Inhibitor II (hydrochloride)	Others; Tyrosine Kinases; Syk; PKC; BTK	Angiogenesis; Chromatin/Epigenetic; Cytoskeletal Signaling; Others; Tyrosine Kinase/Adaptors
	Syk Inhibitor II (hydrochloride) 是一种非受体酪氨酸激酶，磷酸化后，它与 FcRγ 链的基于免疫受体酪氨酸的激活基序结合，并介导与血小板功能和炎症相关的下游信号传导。 Syk inhibitor II 是一种可渗透细胞的嘧啶-甲酰胺化合物，以 ATP 竞争性方式选择性和可逆地阻断 Syk (IC50 = 41 nM)。它对 PKCε、PKCβII、ZAP-70、Btk 和 Itk 的效力要低得多（IC50s 分别为5.1、11、11.2、15.5 和 22.6 μM）。
T4348	Syk Inhibitor II	5-HT Receptor; Syk	Angiogenesis; GPCR/G Protein; Neuroscience; Tyrosine Kinase/Adaptors
	Syk Inhibitor II 是一种可渗透细胞、具有 ATP 竞争性的嘧啶-甲酰胺化合物，可选择性且可逆地抑制 Syk，IC50为 41 nM。
T62691	Syk Inhibitor II dihydrochloride dihydrate
	Syk Inhibitor II dihydrochloride dihydrate 是一种高度选择性的、有效的、ATP 竞争性 Syk 抑制剂 (IC50: 41 nM)。Syk Inhibitor II dihydrochloride dihydrate 抑制 RBL 细胞释放 5-HT (IC50: 460 nM)，对其他激酶的作用较弱。Syk Inhibitor II dihydrochloride dihydrate 表现出抗过敏作用。

化合物

Syk Inhibitor II hydrochloride

Cat.No: T9543

Target: Others

Syk Inhibitor II dihydrochloride

Cat.No: T4391

Synonym: Syk Inhibitor II (hydrochloride)

Target: Others, Tyrosine Kinases, Syk, PKC, BTK

Syk Inhibitor II

Cat.No: T4348

Target: 5-HT Receptor, Syk

Syk Inhibitor II dihydrochloride dihydrate

Cat.No: T62691

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01985	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated FCGR2,FCGR21,CD32A,FCG2,CDw32,CD3...	Human	HEK293 Cells
	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPJ-00803	CD32B Protein, Mouse, Recombinant (His) Fcgr2,Fcgr2b,Fc-γ-RIIB,<...	Mouse	HEK293 Cells
	Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therap...
TMPY-00765	CD32B/Fcgr2b Protein, Human, Recombinant (His) IGFR2,FCGR21,Fc γ RIIB,Fc	Human	HEK293 Cells
	CD32B/Fcgr2b Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.8 kDa and the accession number is P31994-2.

重组蛋白

CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-01985

Species: Human

Expression System: HEK293 Cells

CD32B Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00803

Species: Mouse

Expression System: HEK293 Cells

CD32B/Fcgr2b Protein, Human, Recombinant (His)

Cat.No: TMPY-00765

Species: Human

Expression System: HEK293 Cells

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